University Publications

<p><strong>Background:</strong> Several haemostatic abnormalities (hypercoagulable and hypocoagulable) states have been fully described in hyperthyroidism patients. The current study aimed to measure and assessment of the fibrinogen levels in Hyperthyroidism patient.</p> <p><strong>Materials and Methods:</strong> This is a descriptive case-control study, conducted in January 2016 at Radiation and Isotopes center Khartoum, Khartoum, Sudan. A total of 80 participants were selected for this study, among them 40 known diagnosed Hyperthyroidism patients designated as patient group; their mean age is 42 years. Other 40 participants were volunteer normal healthy group designated ascontrol group; their age matched with patient group. Venous blood sampleswere collected fromboth patients and healthy control group. Blood samples was collected in a container containing 200 &mu;l of 3.2% sodium citrate as anticoagulant, the platelet poor plasma was prepared by centrifuged at 2000 rpm for 15 minutes. Data was collected by structured interview and questionnaire then analyzed by using a computer program statistical package for social sciences (SPSS) version 17.</p> <p><strong>Results:</strong> the present study showed that the fibrinogen levels were significantly elevated in hyperthyroidism patients compared with that normal control group (Mean &plusmn;SD 4.3&plusmn;0.72g/L, with p value 0.00).</p> <p><strong>Conclusion:</strong> This study has shown that the hypercoagulability was present in Sudanese patients with Hyperthyroidism.</p>