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Biochemistry and molecular biology are one of the most important basic sciences that form a part of general biological sciences. Biochemistry is concerned with the chemical reactions and processes that occur in the living cells and molecular biology is concerned with the processes that occur at the molecular level in living cells such as DNA replication and gene regulation.Both of these two sciences are important for medical students to understand the biochemical and molecular basis of diseases, giving them the essential tools to improve the prognosis of patients by creating new biochemical and molecular control over the cells.Solid foundation of biology and chemistry is important for understanding of these large and complex branches of sciences.Understanding of Biochemistry and molecular biology is the main requirement for medical students to be good scientific researchers and to participate in the advance of medical sciences in the world, revolutionizing the way of understanding of diseases

Section 1 (Chemistry):
By the end of this course the student is expected to:
1.    Know  the chemistry of carbohydrates, lipids, proteins, heme and nucleic acids
2.    Recall the mechanism of action of enzymes
3.    Know the different classes of Vitamins and diseases related to their deficiency  
4.    Memorize the different classes of minerals and diseases related to their deficiency 5-Know the daily nutritional requirements for all types of nutrition that essential for maintenance of health
5.    Know the mechanism of oxygen transport by hemoglobin and myoglobin
6.    List the biochemical techniques used in biochemistry labs

Section 2 (Metabolism).
By the end of this course the student is expected to:
1.    Recall the metabolic pathways involved in carbohydrates CHO metabolism and the diseases related to metabolic defects in the different pathways of CHO metabolism
2.    Know the metabolic pathways involved in lipid metabolism and diseases related to defects in the different metabolic pathways of lipid metabolism
3.    Discuss the different metabolic pathways of protein metabolism and clinical conditions related to defective metabolic pathways
4.    Explain the biochemical diseases related to defect in heme metabolism
5.    Discuss the integration of metabolism of the different metabolic pathways and their hormonal regulation
6.    Know the different metabolic pathways related to purine and pyrimidine metabolism and clinical conditions related to their defect
7.    Discuss the metabolic pathways of xenobiotics and clinical conditions related to their defect

Section 3 (Genetics):
By the end of this Semester the student is expected to:
1.    To describe the different phases of cell cycle
2.    To know the structure and nomenclature of chromosomes
3.    To know the process of DNA replication and enzymes involved in this process
4.    To describe the different phases of DNA transcription and post-transcriptional modifications
5.    To list the different protein factors and phases involved in translation and protein synthesis
6.    To describe the mechanisms of regulation of gene expression
7.    To know the different important molecular techniques in genetics and molecular biology
8.    To describe the molecular basis in immunogenetics
9.    To know the molecular basis of carcinogenesis

Section 4 (Molecular biology):
By the end of this course the student is expected to:
1.    To know the Mendalian and non-Mendalian patterns of inheritance
2.    To describe the autosomal and sex-linked disorders
3.    To recall the chromosomal basis of human diseases
4.    To know the incidence of chromosomal abnormalities
5.    To explain the indications of chromosomal analysis
6.    To describe genetic screening and diagnosis
7.    To define the genetic counseling
8.    To know the gene therapy
9.    To describe gene mapping

 

Msc in Biochemistry

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